U.S. flag

An official website of the United States government, Department of Justice.

NCJRS Virtual Library

The Virtual Library houses over 235,000 criminal justice resources, including all known OJP works.
Click here to search the NCJRS Virtual Library

Black Esophagus: Acute Esophageal Necrosis in Fatal Haloperidol Intoxication

NCJ Number
246213
Journal
Journal of Forensic Sciences Volume: 58 Issue: 5 Dated: September 2013 Pages: 1367-1369
Author(s)
Petr Hejna; Michaela Ublova M.D.; Viktor Vorisek Ph.D.
Date Published
September 2013
Length
3 pages
Annotation
Herein, we present a case of 53-year-old psychotic woman with acute esophageal necrosis black esophagus, who was found lying on the floor in the living room of her flat.
Abstract
Herein, we present a case of 53-year-old psychotic woman with acute esophageal necrosis black esophagus, who was found lying on the floor in the living room of her flat. Pillboxes of antipsychotic drugs were located in the bin. External examination of the body was unremarkable. On internal examination, we found acute esophageal necrosis. Histologically, there was complete epithelial necrosis with focal involvement of muscularis mucosae, dense infiltrate of leukocytes, and ulcerations without any viable cells. There was no evidence of underlying organic diseases or trauma. Toxicological analysis revealed a fatal blood level of antipsychotics haloperidol, zotepine, and chlorprothixene. Death of the deceased was attributed to fatal intoxication with three various types of antipsychotics. As far we know, this is the first described association between so-called black esophagus and fatal blood level of neuroleptics. Abstract published by arrangement with Wiley.

Downloads

Availability