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Applications of epigenetic methylation in body fluid identification, age determination and phenotyping

NCJ Number
302740
Journal
Forensic Science International Genetics Supplement Series Volume: 7 Issue: 1 Dated: 2019 Pages: 485-487
Author(s)
Date Published
2019
Length
3 pages
Annotation

In this paper, four different applications are presented in forensic epigenetics using bisulfite modified PCR, HRM, and pyrosequencing. 

Abstract

The first application involves the development of a multiplex amplification capable of simultaneous analysis of four different body fluid/cell types- blood, saliva, sperm, and vaginal epithelia. The authors have also developed a method for the detection of sperm high-resolution melt analysis (HRM). Two other applications involve a determination of suspect age and a biomarker for determining smoking status. (publisher abstract modified)

Date Published: January 1, 2019