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Femur Morphology in Healthy Infants and Young Children

NCJ Number
307155
Journal
Clinical Anatomy Volume: 35 Issue: 3 Dated: Apr 2022 Pages: 305-315
Date Published
April 2022
Length
11 pages
Annotation

This study to characterize femur morphology in healthy infants and young children found that femur length, trochanter width, minimum diaphysis diameter, and growth plate width increased with age and weight, as did structural properties associated with fracture resistance.

Abstract

This study, which aimed to characterize femur morphology in healthy infants and young children, found that femur length, trochanter width, minimum diaphysis diameter and growth plate width increased with age and weight. Structural properties associated with fracture resistance also increased with age and weight. Changes during rapid bone growth are important to understanding fracture risk in infants and young children as they transition to independent walking. Anterior–posterior (AP) radiographs of the femur from children age 0–3 years with no history of bone disease were obtained from two children's hospitals and one medical examiner's office. Femur morphological measures (bone length, minimum diaphysis diameter, growth plate width, and femur radius of curvature) and sectional structural measures were determined. Measures were described and compared based on subject age and mass. Relationships between measures and age and mass were evaluated. The 169 AP femur radiographs were obtained from 99 children (59.6% males, median age = 12.0 months, IQR = 0–27.5 months, median body weight = 10.0 kg, IQR = 4.4–15.6 kg). Femur length (rs = 0.97, p < 0.001; rs = 0.89, p < 0.001), trochanter width (rs = 0.86, p < 0.001; rs = 0.85, p < 0.001), minimum diaphysis diameter (rs = 0.91, p < 0.001; rs = 0.87, p < 0.001), and growth plate width (rs = 0.91, p < 0.001; rs = 0.84, p < 0.001) increased with age and weight, respectively. Cross-sectional area (rs = 0.87; rs = 0.86; p < 0.01), polar moment of inertia (rs = 0.91; rs = 0.87; p < 0.001), moment of inertia (rs = 0.91; rs = 0.87; p < 0.001), polar modulus (rs = 0.91; rs = 0.87; p < 0.001) and medullary canal diameter (rs = 0.83, p < 0.001; rs = 0.73, p < 0.001) at the minimum diaphysis also increased with age and weight, respectively.

Date Published: April 1, 2022