DNA-based human identity testing is conducted by comparison of PCR-amplified polymorphic STR motifs from a known source with the STR profiles obtained from uncertain sources. Samples such as those found at crime scenes often result in a signal that is a composite of incomplete STR profiles from an unknown number of unknown contributors, making interpretation an arduous task. The data for the current study were generated under 144 laboratory conditions and were classified by total copy number and contributor proportions. For the 70 percent of samples that were synthetically compromised, the project reports the level of DNA damage using quantitative and end-point PCR. In addition, it characterized the complexity of the signal by exploring the number of detected alleles in each profile. (publisher abstract modified)
Downloads
Similar Publications
- Solving Cases of Sudden Unexpected Natural Death in the Young through Comprehensive Postmortem Genetic Testing
- In Vitro Structure-activity Relationships and Forensic Case Series of Emerging 2-benzylbenzimidazole 'Nitazene' Opioids
- Stage Transitions in Lucilia sericata and Phormia regina (Diptera: Calliphoridae) and Implications for Forensic Science