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Cardiovascular Conditions and the Evaluation of the Heart in Pregnancy-Associated Autopsies

NCJ Number
232887
Journal
Journal of Forensic Sciences Volume: 55 Issue: 6 Dated: November 2010 Pages: 1528-1533
Author(s)
Jonathon Herbst, M.D.; Calle Winskog, M.D.; Roger W. Byard, M.B.B.S., M.D.
Date Published
November 2010
Length
6 pages
Annotation
Pregnancy-associated death is defined as the death of a woman from any cause during pregnancy or in the year after delivery. This review concentrates on cardiac conditions that may result in pregnancy-associated death including, but not limited to, acute myocardial infarction, endocarditis, peripartum cardiomyopathy, and prolonged QT syndrome.
Abstract
Lethal vascular conditions may also occur involving arterial dissection and thromboembolism, on occasion exacerbated by hypercoagulability, and altered hormonal and physiologic states. The autopsy evaluation of these patients includes a careful assessment of the medical history particularly for prior pregnancy-related conditions, fetal loss, and episodes of unexplained collapse. A family history of sudden death at an early age may be significant. At autopsy, evaluation for underlying syndromes such as Marfan, or evidence of intravenous narcotism should be undertaken. Autopsy examination involves careful dissection of the heart and vessels with consideration of conduction tract studies and possible genetic evaluation for prolonged QT syndrome. (Published Abstract)