NCJ Number
56888
Journal
JOURNAL OF THE IRISH MEDICAL ASSOCIATION Volume: 63 Issue: 400 Dated: (OCTOBER 1970) Pages: 362-364
Date Published
1970
Length
3 pages
Annotation
THIS STUDY INVESTIGATES THE PREVALENCE OF CYTOGENETIC ABNORMALITIES IN THE POPULATION OF AN IRISH MAXIMUM SECURITY HOSPITAL--81 MALES AND 15 FEMALES.
Abstract
BLOOD SAMPLES FOR EACH OF THE 96 PATIENTS WERE TAKEN, AND BLOOD FILMS WERE PREPARED AND STAINED. LEUCOCYTE CULTURES WERE HARVESTED AT 46 HOURS. THESE STAINS AND BUCCAL SMEARS FOR THE SUBJECTS WERE STAINED WITH ACETIC ORCEIN. TWO HUNDRED POLYMORPHONUCLEAR NEUTROPHILS AND TWO HUNDRED BUCCAL MUCOSAL CELLS WERE EXAMINED FOR EACH SUBJECT, AND EACH SUBJECT'S HEIGHT WAS NOTED. RESULTS SHOW THAT ONLY ONE PATIENT, A MALE, WAS TALLER THAN 183 CENTIMETERS AND THAT NONE OF THE SUBJECTS HAD AN XYY KARYOTYPE OR ANY OTHER CHROMOSOME ABNORMALITY. ONE MALE DID HAVE AN UNUSUALLY LARGE Y CHROMOSOME. THE FINDING THAT NO MALES HAD EXTRA Y CHROMOSOMES IS SOMEWHAT SIGNIFICANT IN THAT NONE OF THE SUBJECTS WERE TALL AND TALLNESS IS ASSOCIATED WITH THE XYY KARYOTYPE. TABULAR DATA AND REFERENCES ARE PROVIDED. (DAG)