Hair Analysis for Drug Abuse: I. Determination of Methamphetamine and Amphetamine in Hair by Stable Isotope Dilution Gas Chromatography/Mass Spectrometry Method

• NCJ Number: 128088
• Journal: Journal of Forensic Sciences Volume: 36 Issue: 1 Dated: (January 1991) Pages: 70-78
• Author(s): Y Nakahara; K Takahashi; M Shimamine; Y Takeda
• Date Published: 1991
• Length: 9 pages
• Publication Format: Article
• Publication Type: Research (Applied/Empirical)
• Language: English
• Country: United States of America

Annotation

An analysis of the presence of metamphetamine (MA) and amphetamine (AP) in monkey and human hair is performed by isotype dilution gas chromatography/mass spectrometry (GS/MS) using deuterium-labeled MA and AP.

Abstract

The experimental materials described consist of reagants, hair sample, apparatus, 2-methylamino-1-Phenylpropane-2,3,3,3-d, (MA-d), and 2-Amino-1-Phenylpropane-2,3,3,3-d (AP-d). The results discussed in this article relate to calibration curves, linearity, reproducibility, and washing; the two extraction methods outlined include external contamination of hair samples and sectional analysis of hair samples. The results suggest that there is a good correlation between the duration of drug use and sectional drug distribution in hair. 3 tables, 3 figures, and 11 references (Author abstract modified)