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Increasing Phylogenetic Resolution Still Informative for Y Chromosomal Studies on West-European Populations

NCJ Number
245549
Journal
Forensic Science International: Genetics Volume: 9 Dated: March 2014 Pages: 179-185
Author(s)
M.H.D. Larmuseau; N. Vanderheyden; A. Van Geystelen; M. van Oven; M. Kayser; R. Decorte
Date Published
March 2014
Length
7 pages
Annotation
Since many Y-chromosomal lineages defined in the latest phylogenetic tree of the human Y chromosome in 2008 by the Y-Chromosome Consortium (YCC) are distributed in Western Europe, this study examined whether the new Y-chromosome tree shows greater diversity in the male population in the West-European region of Flanders (Belgium).
Abstract
The findings suggest that the update of the Y-chromosomal tree based on new polymorphisms provides a better discrimination between males in Flanders based on Y-SNPs. Thus, population genetic patterns can be identified in more detail even in an already well-studied region such as Western Europe. Based on these results, there is apparently a larger intra- and intercontinental differentiation than previously observed based on the sub-haplogroups R-U106 and U152. Frequency distribution maps for markers such as L48 and Z381, for which strong spatial differentiation was observed within Flanders, are therefore relevant. Flanders was selected for the study area since more than 1,000 Y-chromosomes from this area have previously been genotyped at the highest resolution of the 2008 YCC tree and coupled to in-depth genealogical data. Based on these data, the temporal changes of the population genetic pattern over the last centuries within Flanders were studied, and the effects of several past gene flow events were identified. 5 figures, 2 tables, and 34 references