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LYSERGIC ACID DIETHYLAMIDE (LSD)

NCJ Number
144305
Journal
Pharmchem Technical Bulletin Volume: 3 Issue: 1 Dated: (Spring 1993)
Editor(s)
M Moore
Date Published
1993
Length
2 pages
Annotation
The availability and abuse of lysergic acid diethylamide (LSD) is increasing in the U.S., according to the Drug Enforcement Administration (DEA), which made nearly four times the number of LSD-related arrests in 1992 (393) as in 1989 (102).
Abstract
The low cost of LSD seems to appeal to high school students, even as they reportedly curtail their use of marijuana and cocaine. LSD, which belongs to a group of compounds known as ergot alkaloids, is a very powerful hallucinogenic, thought to affect the sertonergic nervous system. Oral doses result in many symptoms including dizziness, weakness, drowsiness, euphoria, sensory illusions, and affective changes. Low doses taken repeatedly over time may produce a tolerance to LSD, which means that the user develops a state of increasing resistance to the usual effects of the drug as a result of prior exposure. The lethal dosage of LSD is still unknown. The DEA believes there are only a dozen American LSD manufacturers, centered in the Northwest; San Francisco is the primary distribution point for the U.S. and most of the world. 2 figures

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