Polymorphism of Complement Factor I: Population Study in Japanese and Phenotyping in Bloodstains

• NCJ Number: 136675
• Journal: Japanese Journal of Legal Medicine Volume: 45 Issue: 5-6 Dated: (December 1991) Pages: 400-403
• Author(s): Y Dobashi; K Hashimoto; N Komatsu; A Kido; Y Kimura; M Oya
• Date Published: 1991
• Length: 4 pages
• Publication Format: Article
• Publication Type: Report (Technical)
• Language: English
• Country: Japan

Annotation

The polymorphism of the human complement component factor I (IF) was examined in 645 unrelated Japanese individuals using isoelectric focusing and immunoblotting to determine its usefulness in identifying bloodstains in medical and forensic situations.

Abstract

Previous studies had shown that IF exhibits a relatively large variation among Asians, but not among Causasians. The results of the current research revealed population data that fitted the Hardy-Weinberg law. In addition, phenotyping was possible using bloodstains that had been stored at 37 degrees Celsius for up to 1 week, at room temperature for up to 2 weeks, and at 4 degrees Celsius for up to 5 weeks. Findings indicated that the IF system can be a useful supplement for the forensic identification of bloodstains, although it seems useless for identifying Caucasians. Figures, tables, and 8 references (Author abstract modified)