NCJ Number
138648
Journal
Canadian Society of Forensic Science Journal Volume: 25 Issue: 2 Dated: (June 1992) Pages: 71-78
Date Published
1992
Length
8 pages
Annotation
This article reports on an examination of the phenotypic distribution of the polymorphic enzyme alpha- L fucosidase (AlFuc) in 1,223 random human samples provided by a New York City-based fertility clinic.
Abstract
The calculated FUC allele frequencies reported in several studies suggest that AlFuc is a useful marker for forensic purposes as well as for studies in population genetics. Although FUC gene frequencies have been studied in many different populations and in several different tissues, the study reported in this article is the first that has determined the distribution of the seminal phenotypes in a New York City population. Untreated semen samples as well as specimens pretreated with neuraminidase were analyzed by IEF. Samples were run on a 1.0-mm by 15-cm by 20-cm gel that contained Amphline in the range of pH 5 to 7. Three phenotypes -- AlFuc 1, AlFuc 2, and AlFuc 2-1 -- were observed. The allele frequencies of FUC 1 and FUC 2 were calculated as 0.695 and 0.305 respectively. There was no significant difference between these frequencies and those reported for other populations, with the exception of the United States black and French populations. 3 figures, 2 tables, and 16 references