NCJ Number
3035
Date Published
1969
Length
19 pages
Annotation
STUDY OF THE SKIN SENSITIZATION CAPACITY OF OCHLOROBENZYLIDENE MALONONITRILE AND THREE OTHER RIOT CONTROL AGENTS IN GUINEA PIGS.
Abstract
IT HAS BEEN REPORTED THAT O-CHLOROBENZYLIDENE MALONONITRILE (CS) SHOWED EVIDENCE OF A SKIN-SENSITIZING POTENTIAL IN MAN. THIS PROMPTED A BASIC STUDY OF THE SKIN SENSITIZATION CAPACITY OF CS AND THREE OTHER RIOT CONTROL AGENTS IN GUINEA PIGS. IT WAS CONCLUDED THAT - NEITHER CA NOR DM PRODUCES SKIN SENSITIZATION IN GUINEA PIGS WHEN ADMINISTERED INTRADERMALLY. BOTH CN AND CS PRODUCE SKIN SENSITIZATION IN GUINEA PIGS WHEN ADMINISTERED INTRADERMALLY OR TOPICALLY.