TREATMENT OF YOUNG DELINQUENT BOYS WITH DIPHENYLHYDANTOIN SODIUM AND METHYPHENIDATE

• NCJ Number: 55091
• Journal: Archives of General Psychiatry Volume: 24 Dated: (FEBRUARY 1971) Pages: 156-160
• Author(s): C K CONNERS; R KRAMER; G H ROTHSCHILD; L SCHWARTZ; A STONE
• Date Published: 1971
• Length: 5 pages
• Corporate Author: American Medical Assoc
• Publication Format: Article
• Publication Type: Report (Study/Research)
• Language: English
• Country: United States of America

Annotation

FORTY-THREE JUVENILE DELINQUENT MALES, RESIDING IN THE MARYLAND TRAINING SCHOOL, WERE SELECTED FROM 52 NOMINATED CASES AND TREATED WITH EITHER DIPHENYLHYDANTOIN SODIUM, METHYLPHENIDATE, OR PLACEBO.

Abstract

THE 43 DELINQUENTS WERE RANDOMLY ASSIGNED TO DOUBLE-BLIND TREATMENT FOR 2 WEEKS. RATINGS OF SYMPTOMS BY COTTAGE PARENTS AND TEACHERS, A MEASURE OF FRUSTRATION, THE PORTEUS MAZES, AND AN INTERVIEW WERE USED TO ASSESS THE EFFECTS OF THE TREATMENTS. NONE OF THE MEASURES SHOWED EFFECTS ATTRIBUTABLE TO THE DRUGS, AND SUBJECTIVE REPORTS TENDED TO SHOW NEGATIVE EFFECTS OF THE ACTIVE DRUGS. THE DANGER OF RANDOM ASSIGNMENT STUDIES WAS DEMONSTRATED, HOWEVER, BY THE FACT THAT THE MORE DISTURBED CHILDREN WERE ASSIGNED BY CHANCE TO THE PLACEBO GROUP. THE LACK OF SEVERE SYMPTOMATOLOGY, THE SHORT PERIOD OF TREATMENT, AND THE HETEROGENEOUS NATURE OF THE SAMPLE WERE CONSIDERED AS POSSIBLE EXPLANATIONS OF THE APPARENT LACK OF BENEFICIAL OUTCOMES EFFECTED BY THE TWO DRUGS. REFERENCES AND TABULAR DATA ARE PROVIDED. (AUTHOR ABSTRACT MODIFIED--KBL)